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RESEARCH

Here are links to research studies and sites that provide information to help you understand Lyme complex. Please check back as we continue to expand this collection. 

Psychiatric symptoms 

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Physical Systoms

New compounds have potential to combat Lyme disease, Stanford University 

In Search of a cure for Lyme disease: The Disulfiram Story 

“Repurposing” Disulfiram in the Treatment of Lyme Disease and Babesiosis:

​Retrospective Review of First 3 Years’ Experience in One Medical Practice, Dr. Kenneth Liegner 2020 

 
Repurposing disulfiram (Tetraethylthiuram Disulfide) as a potential drug candidate against Borrelia burgdorferi in vitro and in vivo 

Disulfiram (Tetraethylthiuram Disulfide) in the Treatment of Lyme Disease and Babesiosis: Report of Experience in Three Cases

Resources

Dr. Rosalie Greenberg’s Blog, child psychiatrist and Lyme specialist 

Dr Jane Marke, adult psychiatrist, physician training on psychiatric symptoms of Lyme (case studies at 35 minutes)  

Galaxy patient stories

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What if you still have symptoms after treatment?

There is a debate among some doctors that persistent Lyme (long-haul Lyme) does not exist. These doctors believe once a short bout of doxycycline is given, you should be cured and that lingering symptoms are post treatment Lyme for which there is no treatment or known etymology. Clinically it has been shown that additional treatment is beneficial and can bring Lyme complex to remission in some patients. If you find yourself in this situation, find a Lyme specialist (on this page) to evaluate your symptoms and recommend next steps. 
 

Peer-Reviewed Evidence of Persistence of Lyme Disease Spirochete Borrelia burgdorferi and Tick-Borne Diseases  

Persister Development by Borrelia burgdorferi Populations In Vitro 

Borrelia burgdorferi, the Causative Agent of Lyme Disease, Forms Drug-Tolerant Persister Cells 

Spatial and Temporal Comparison of Perceived Risks and Confirmed Cases of Lyme Disease: An Exploratory Study of Google Trends

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Disulfiram

Disulfiram is an important, recent drug discovery in the treatment of borrelia and babesia. In 2016, Dr. Jayakumar Rajadas studied the efficacy of 4,000 existing drugs in the treatment of borrelia and babesia. Disulfiram was identified as the top treatment and eradicated these microorganisms in lab and mouse studies. Patient treatment began in 2018 and has continued to pick up steam as more patients have had success, even in difficult cases with years of failed treatment. 

 

News (could be icon) New compounds have potential to combat Lyme disease, Stanford University 

 

News (icon) In Search of a cure for Lyme disease: The Disulfiram Story 

 

“Repurposing” Disulfiram in the Treatment of Lyme Disease and Babesiosis:

​Retrospective Review of First 3 Years’ Experience in One Medical Practice, Dr. Kenneth Liegner 2020 

 

Repurposing disulfiram (Tetraethylthiuram Disulfide) as a potential drug candidate against Borrelia burgdorferi in vitro and in vivo 

Disulfiram (Tetraethylthiuram Disulfide) in the Treatment of Lyme Disease and Babesiosis: Report of Experience in Three Cases

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